Zendaya looked downcast as she left the set of her smash hit HBO show Euphoria after a hard day’s work this week.

The 28-year-old actress has returned to the role of teenage drug addict Rue Bennett, amid a cast that includes Sydney Sweeney, Jacob Elordi and Colman Domingo.

When she was seen working on the show in Los Angeles this Wednesday, Zendaya was bundled up against the lingering chill in a maroon hoodie.

Wearing her luxurious hair down, the Dune star – who recently got engaged to her longtime beau Tom Holland – opted for minimal makeup. 

Her latest sighting comes on the heels of the heartbreaking news that her co-star Eric Dane has been diagnosed with amyotrophic lateral sclerosis (ALS).

In spite of his illness, Eric confirmed he will continue acting on Euphoria in the villainous role of Cal Jacobs, the domineering father of Jacob’s character Nate.

Zendaya looked downcast as she left the set of her smash hit HBO show Euphoria after a hard day’s work this week

Although Zendaya has not publicly addressed Eric’s health problems, their castmate Colman Domingo expressed support for the Grey’s Anatomy actor.

‘I haven’t been able to speak with him yet,’ he told People last Friday. ‘I just got the news yesterday too, and I’m wishing him well. I look forward to working with him.’

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Eric shatteringly announced last week that he is suffering from ALS, a rare and incurable degenerative condition that impairs the nervous system over time and causes the muscles to increasingly suffer from paralysis.

About half of ALS patients have a life expectancy of three years after the initial onset of symptoms, though some can survive for decades. 

‘I have been diagnosed with ALS,’ Eric, 52, said in a statement to People. ‘I am grateful to have my loving family by my side as we navigate this next chapter.’

The news comes a month after Eric and his wife Rebecca Gayheart – with whom he shares daughters Billie, 15, and Georgia, 13 – called off their divorce.

‘I feel fortunate that I am able to continue working and am looking forward to returning to set of Euphoria next week,’ said Eric, a longstanding star of the HBO series. ‘I kindly ask that you give my family and I privacy during this time.’

ALS has been colloquially known in America as Lou Gehrig’s disease ever since it claimed the life of the beloved baseball player in 1941 when he was just 37. 

When she was seen working on the show in Los Angeles this Wednesday, Zendaya was bundled up against the lingering chill in a maroon hoodie

Grey’s Anatomy star Eric Dane has heartbreakingly revealed that he has been diagnosed with amyotrophic lateral sclerosis (ALS); pictured last May

The cause of ALS is a process called neurodegeneration, in which motor neurones – specialist nerve cells in the brain and spine – begin to malfunction.

Most people with ALS only start exhibiting symptoms in their 60s, though in very rare cases the condition can develop in people as early as their teenage years.

Early symptoms can include weakness in one limb that then spreads to a different one, or difficulty swallowing, or slurred speech, via Johns Hopkins Medicine.

Over time, patients may start falling down, suffering from fatigue, losing motor skills, laughing or crying uncontrollably or feeling their muscles twitch and cramp.

When the condition advances even further, someone with ALS can experience paralysis and have difficulty with functions as basic as swallowing or breathing.