Jason Isaacs sniped at Rebel Wilson when she made a joke about his full-frontal nudity scene in The White Lotus.

The Harry Potter star, 61, took on the role of Timothy Ratcliff in the smash hit drama and one scene saw him accidentally expose his genitals while sitting in a bathrobe.

While his kids Piper (Sarah Catherine Hook) and Lochlan (Sam Nivola) were shocked, his wife Victoria (Parker Posey) and son Saxon (Patrick Schwarzenegger) laughed.

The ɴuᴅᴇ scene became highly talked about and Jason has been repeatedly quizzed on whether he used a prosthetic penis, with his co-stars confirming he did.

Jason has made it clear he doesn’t like being asked about the nudity and once again shut down questioning on it during an appearance on The Jonathan Ross Show.

On the show, which is set to air on Saturday night, comedian Rebel, 45, made a joke about his full-frontal nudity, which seemingly didn’t go down well with Jason.

Jason Isaacs sniped at Rebel Wilson (pictured) when she made a joke about his full-frontal nudity scene in The White Lotus

The Harry Potter star, 61, took on the role of Timothy Ratcliff in the smash hit drama and one scene saw him accidentally expose his genitals while sitting in a bathrobe

As Jason discussed The White Lotus’ success, Rebel quipped: ‘I liked the stripping down bit…’ referring to his ɴuᴅᴇ scene.

But Jason quickly shut down her remark as he replied: ‘The show is so fabulous, seems a bit odd to talk about my d*** the whole time…’

Jason also addressed rumours of behind-the-scenes tension on the Thailand set of the HBO drama as he admitted there were some ‘weird people’ who didn’t socialise.

‘You do see people all the time. Some people didn’t leave the H๏τel, some didn’t leave their room,’ he said.

‘There were some weird people. Never appeared socially. What happened in Thailand stays in Thailand.’ 

When pressed on who he was referring to, Jason cryptically replied: ‘It might not be a member of the cast.’

He admitted it was ‘very intense’ living in Thailand with the entire cast and crew for seven months, but gushed that he bonded very closely with his on-screen family.

‘You’d normally have an apartment or a house. We got to know each other very well. The people in my family, my screen kids, I fell madly in love with,’ he shared.

Jason has made it clear he doesn’t like being asked about the nudity and once again shut down questioning on it during an appearance on The Jonathan Ross Show

When Rebel joked that she ‘liked the stripping down bit’, Jason hit back with: ‘The show is so fabulous, seems a bit odd to talk about my d*** the whole time’

Read MoreEXCLUSIVE The tangled friendships on The White Lotus set as rumours swirl over cast feud

It is not the first time Jason has addressed rumours of tension on set, with co-star Aimee Lou Wood playfully taking aim at him for ‘oversharing’ about the dynamics.

Jason recently summed up the shoot as ‘a cross between summer camp and Lord of the Flies but in a gilded cage’, with Aimee re-sharing a joke about it to Instagram. 

Reposting a meme of someone who spills all of their secrets without even being asked alongside the words: ‘Interviewer: so did you enjoy Thailand? Jason Isaacs:….’

Aimee Lou, who played the tragic fan favourite Chelsea, has herself described living on the same resort where filming took place as like being on the Truman Show.

She has been hit by rumours that she fell out with Walton Goggins – who played her on-screen lover Rick Hatchett – as they unfollowed each other on Instagram after becoming close friends on set.

Though filming in Thailand came with its tensions, Jason also praised creator Mike White as a ‘phenomenal human being’.

He said of the director: ‘He laughs, shouts out the most insane things for you to try.  We all fold in like an improv troupe. A lot of it ends up in the show.’

Jason also discussed his popular role as Lucius Malfoy in the original Harry Potter movie franchise and who might take over his role in the upcoming TV adaptation.

Jason also addressed rumours of behind-the-scenes tension on the Thailand set of the HBO drama as he admitted there were some ‘weird people’ who didn’t socialise

It is not the first time Jason has addressed rumours of tension on set, with Aimee Lou Wood playfully taking aim at him for ‘oversharing’ amid rumours she fell out with Walton Goggins 

Jason appeared on The Jonathan Ross Show alongside (L-R) Sophie Willan, David Oyelowo, Andrew ‘Freddie’ Flintoff and Rebel Wilson

HBO will be recreating the popular wizarding novels by JK Rowling in a brand new series, which is set to begin filming this summer.

Some of the star-studded cast have already been announced, with John Lithgow starring as Albus Dumbledore and Nick Frost taking on the role of Rubeus Hagrid. 

It is not yet known who will be playing Death Eater Lucius, the father of Harry Potter’s nemesis Draco Malfoy, though Jason has thrown a name into the ring.

He suggested Danny Dyer take over the role, before adding: ‘Soon I’ll be pᴀssing the torch on. Fantastic actors [are] being cast. 

‘It’s going to be great and [being recognised] won’t happen anymore.’

However, Jason admitted he is rarely ever recognised in public by young children who are fans of the franchise.

‘They don’t really recognise me, I rarely walk around with an elf,’ he quipped.

The Jonathan Ross Show airs on Saturday at 10.20pm on ITV1, ITVX, STV and STV Player.