Scrubs star Eliza Coupe looked unrecognizable nearly 15 years after the highly-popular sitcom went off air.

The 43-year-old actress attended the premiere for Netflix series The Residence – which included an Orange Is The New Black reunion –  in Hollywood on Wednesday night.

She glittered in a low-cut shimmering metallic gold dress at the star-studded event held at The Egyptian Theater.

The Plymouth, New Hampshire native teamed the shiny frock with a pair of black suede knee high booties.

She also wore a black mink coat but draped it down her arms to show off more of the dress while posing on the blue carpet.

Her blonde locks were worn down as the fringe hung to just above her eye as her make-up was highlighted by a smokey eye.

Scrubs star Eliza Coupe looked unrecognizable nearly 15 years after the highly-popular sitcom went off air

Eliza looked much different than her days starring as Denise ‘Jo’ Mahoney on the last two seasons of Scrubs – eight and nine – which aired in 2009 and 2010

Eliza looked much different than her days starring as Denise ‘Jo’ Mahoney on the last two seasons of Scrubs – eight and nine – which aired in 2009 and 2010.

Her character was an intern at Sacred Heart Hospital in season eight. She is outspoken and brutally honest, and struggles with patient-doctor communications because of this. 

Read More Netflix fans go wild as Orange Is The New Black cast has epic reunion

In season nine, she is a resident at the new Sacred Heart Hospital, as well as a student adviser and teacher’s ᴀssistant at Winston University. She is romantically involved with medical student Drew Suffin. 

Scrubs was a medical sitcom created by Bill Lawrence and aired from October 2001 to March 2010 as it followed the lives of employees at the fictional Sacred Heart Hospital which is a teaching hospital.

Eliza has found a lot of success in sitcoms as she is also known for starring as Jane Kerkovich-Williams in the ABC comedy series Happy Endings.

The character  was compeтιтive, a perfectionist by nature, and something of a control freak. 

Despite her Type-A atтιтude, Jane had a wild past in college, most notably embracing her biSєxuality, wearing pink streaks in her hair, and donating an egg her freshman year to finance a spring break trip to Cabo San Lucas.

Happy Endings was a single-camera ensemble comedy which aired over three seasons from April 2011 to May 2013. 

The 43-year-old actress attended the premiere for Netflix series The Residence – which included an Orange Is The New Black reunion – in Hollywood on Wednesday night

She glittered in a low-cut shimmering metallic gold dress at the star-studded event held at The Egyptian Theater

The Plymouth, New Hampshire native teamed the shiny frock with a pair of black suede knee high booties.

She also wore a black mink coat but draped it down her arms to show off more of the dress while posing on the blue carpet.

Her blonde locks were worn down as the fringe hung to just above her eye as her make-up was highlighted by a smokey eye

In her latest project, she portrays a character named Margery Bay Bix in the series which centers around the inside of the White House staff residence and the lives that the workers share with the First Family

Eliza (right) has found a lot of success in sitcoms as she is also known for starring as Jane Kerkovich-Williams in the ABC comedy series Happy Endings; she is pictured with Briga Heelan

Meanwhile her latest project The Residence is a mystery drama series created by Paul William Davies.

She portrays a character named Margery Bay Bix in the series which centers around the inside of the White House staff residence and the lives that the workers share with the First Family.

Orange Is The New Black star Uzo Aduba leads the cast which also features Barrett Foa, Edwina Findley, Juliette Jeffers, Al Mitchell, Bret Tucker, Jodi Bianca Wise, Paul Fitzgerald, Sumalee Montano, J.D. Hall, Julieth Restrepo, and James Babson.